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Permanent Present Tense: The Unforgettable Life of the Amnesic Patient, H.M.
Download Ebook Permanent Present Tense: The Unforgettable Life of the Amnesic Patient, H.M.
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Audible Audiobook
Listening Length: 13 hours and 15 minutes
Program Type: Audiobook
Version: Unabridged
Publisher: HighBridge, a division of Recorded Books
Audible.com Release Date: May 14, 2013
Whispersync for Voice: Ready
Language: English, English
ASIN: B00CQABZL0
Amazon Best Sellers Rank:
I have read about amnesia patient H.B. (Henry Molaison) for a long time and was very interested when the psychologist who was able to work with him for over 4 decades would be writing a biography of him. I have cognitive memory issues of my own and thought if I could read about how he compensated for his missing memory to live to over 80 years-old, it could be beneficial to my own understanding of memory. While the author Corkin did include many human elements in describing the long and well-researched life of H.B. after his brain surgery left him with permanent amnesia, she is a professor and writes at a level that her college and graduate students would read at, including many medical and neuropsychological terms that were a little hard to understand even though I am a college graduate and have had some experience in grad school.I think this book is written more for the memory researcher or psychoanalyst who wants more information about the most famous and well-studied brain in the world up to the present time and not so much for the general layperson with a casual interest who might find the story of H.B.'s life interesting and compelling for the human elements. I would recommend this book for anyone looking to increase their understanding of memory and what regions of the brain do what for different cognitive processes in a semi-professional way, but it will be a fairly hard read for anyone who is not really into the subject and committed to working through the professional lingo peppered throughout the book.
This is a truly remarkable book about the most famous patient in neuroscience - Patient H.M. - written by his bona-fide scientific guardian Dr. Suzanne Corkin . All students of Neuroscience know about H.M. and his anterograde amnesia due to the surgical removal of his hippocampi, but there are much more fascinating details to be learned!For example, did you know that H.M.'s amygdala were also completely removed? That he could still express a full range of emotions without the amygdala, but he had deficits in judging internal states such as hunger, thirst, and pain? Did you know that H.M. also suffered retrograde amnesia that extended backwards to almost 15 years before the surgery? H.M. was sometimes able to learn and remember certain information after his surgery, which surprised Dr. Corkin and prompted her to conduct further experiments to find out the causes. Dr. Corkin's research investigated not only the declarative memory deficits of H.M., but probed the emotion, sleep, motor skills, priming effects, and various other intricacies of learning and memory. In the book, Dr. Corkin goes into comprehensive details of her experiments, complete with the rationale and the scientific background for her experimental designs. One can learn a tremendous amount about memory research and neuroscience in general just by reading this book.Overall, this is a fascinating read. The narrative is well-written and engaging; I read the whole book cover-to-cover at once. My only minor criticisms are that 1) there could be better graphs and diagrams, and I'd appreciate more high-quality photos of the main star, Henry Molaison; and 2) names of collaborating researchers and scientists are selectively mentioned or omitted, it would be better to either mention all the names (instead of eg. a researcher at UCSD) or at least cite the names in the footnotes to give proper credit/recognition. Otherwise, this is a fascinating account of the memorable life of H.M. and of the remarkable achievements of Dr. Corkin and her colleagues!
It isn't often that you can tell the history of a field through the history of one man. But H.M could claim that honor for memory neuroscience. After going through a bilateral medial temporal-lobe resection to cure his petit mal seizures from childhood epilepsy - H.M was unable to form any new long-term memories. He specifically lacked declarative memory, memories where people can openly state what they have learned. He lost his temporal lobe, the right temporal lobe processes visual-spatial info and the right verbal info - with neural bridges providing each other with information. Anyone who has taken a course in memory will now recognize an entire world behind a simple textbook case-study mentioned in a chapter. We're privileged to have this book - but what about F.C, P.B, K.F, N.B and P.Z ? Who knows if someone will do them justice by documenting the real lives behind the case study.We know so many things about memory and about being human, how it determines our self and identity, how relationships depend on common memories - but all this abstract pondering comes to life when you look at a real-life case and how someone copes in the light of losing his humanity. It also sheds light into the recklessness of medicine during the height of psychosurgery, and how the discrete/modular view of the neural underpinnings of certain abnormalities resulted in scientists feeling that certain brain areas could be removed to cure so and so problem. The worst-case scenario can be seen when Walter Freeman operated twenty-five women a day. What is slightly disturbing is that the baton has now been passed to pharmacology, and misdiagnoses and overmedicating are simply modern-day examples of similar medical irresponsibility.H.M was really useful because he didn't suffer from any psychiatric disorder and his amnesia didn't affect cognitive performance on non-memory task - so experimental data could be isolated as the causal result of amnesia. The beauty of the Henry Molaisson was that his case revolved around so many important topics, such as the acquisition of episodic (events in certain time and place) and semantic (meanings) knowledge. For example, it was via such cases that we saw that the hippocampus is responsible for word associations.This book is very academic, and is primarily for those that have done their studies in the cognitive scientists. A regular reader wouldn't know what to make of the information or the larger picture behind the mentioned science. If you were expecting a biography, the chapter "Henry's Universe" is probably all you'll get. Its hard to write about the "most comprehensively studied patient in neuroscience" without introducing one to the history of the field and how it developed as H.M. aged.Rereadable and endlessly engrossing, can be read as a history of memory neuroscience. It tells you about the ecstasy when you find an opportunity for scientific discovery, perfectly captured by the hurried attempt to image the Henry's brain after he died to get a clear picture of his brain. The history of science owes this book a lot!
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